Lab Leak Plausible(Critical Review)[2021]

Holmes et al. have written an extensive argument for a natural origin of SARS-CoV-2 and importantly urge a comprehensive, collaborative, and careful investigation of possible zoonotic origins of the virus. However, their review does not address plausible lab origin scenarios where a virus may have infected a researcher during fieldwork or in the lab. It is too confident in dismissing the possibility that the virus may have been cultured, manipulated, and even engineered or recombined in the laboratory without leaving obvious signs of human interference. Techniques to synthesize entire virus genomes without leaving traces have existed for years and have been used by labs around the world; these can easily evade detection strategies devised by scientists, especially when not all viruses and sequences being studied in labs are shared publicly in a timely manner [80,81].

https://ayjchan.medium.com/a-response-to-the-origins-of-sars-cov-2-a-critical-review-5d4a644d9777