COVID

Number of coronavirus deaths US by age (Statista)[2022]

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https://www.statista.com/statistics/1191568/reported-deaths-from-covid-by-age-us/

Innate immune suppression by SARS-CoV-2 mRNA vaccinations(NCBI)[2022]

The mRNA SARS-CoV-2 vaccines were brought to market in response to the public health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein. However, the immune response to the vaccine is very different from that to a SARS-CoV-2 infection. In this paper, we present evidence that vaccination induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health. Immune cells that have taken up the vaccine nanoparticles release into circulation large numbers of exosomes containing spike protein along with critical microRNAs that induce a signaling response in recipient cells at distant sites. We also identify potential profound disturbances in regulatory control of protein synthesis and cancer surveillance. These disturbances potentially have a causal link to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell's palsy, liver disease, impaired adaptive immunity, impaired DNA damage response and tumorigenesis. We show evidence from the VAERS database supporting our hypothesis. We believe a comprehensive risk/benefit assessment of the mRNA vaccines questions them as positive contributors to public health.

 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9012513/

Adverse Event Reports (phmpt)[2021]

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https://phmpt.org/wp-content/uploads/2021/11/5.3.6-postmarketing-experience.pdf

J&J Wanes After 6 Months(Study)[2021]

The November study, published in Science, examined COVID-19 infection and deaths by vaccination status of more than 780,000 U.S. Veterans. Researchers from the Public Health Institute, the Veterans Affairs Medical Center, and the University of Texas Health Science Center compared the vaccine's effectiveness in March to that in September.

They found that the Pfizer-BioNTech vaccine’s effectiveness against infection dropped to 43.3% from 86.9% after six months. The Moderna vaccine saw a similar decline, falling to 58.0% from 89.2%. They observed the largest drop in the Johnson & Johnson vaccine, which was 13.1% effective in September compared to 86.4% in March.

 

https://www.verywellhealth.com/vaccine-covid-effectiveness-5209145

https://www.science.org/doi/10.1126/science.abm0620

https://www.whitehouse.gov/briefing-room/press-briefings/2021/08/18/press-briefing-by-white-house-covid-19-response-team-and-public-health-officials-50/

 

 

VAERS Estimate 388,000 Americans Killed by COVID Vaccines

My estimate of the VAERS under-reporting factor (URF) at 41 was based on anaphylaxis rates reported in the Blumenthal paper published in JAMA.

I have argued that the anaphylaxis rate is an appropriate number to use to (under) estimate deaths because I believed that deaths would be less reported than anaphylaxis to VAERS for two reasons: 1) usually lacks the time proximity to vaccination, 2) the person seeing the death may not know the vaccination status of the victim and may not technically be required to report the death.

https://stevekirsch.substack.com/p/latest-vaers-estimate-388000-americans?r=o7iqo&utm_campaign=post&utm_medium=web&s=r

 

How do Viruses Mutate(Pfizer)

From what has been observed thus far regarding the genetic evolution of SARS-CoV-2, it appears that the virus is mutating relatively slowly as compared to other RNA viruses. Scientists think this is due to its ability to “proofread” newly made RNA copies This proofreading function does not exist in most other RNA viruses, including influenza. Studies to date estimate that the novel coronavirus mutates at a rate approximately four times slower than the influenza virus, also known as the seasonal flu virus. Although SARS-CoV-2 is mutating, thus far, it does not seem to be drifting antigenically. It should be noted, however, that SARS-CoV-2 is a newly discovered virus infecting humans. There are still many unknowns, and our understanding of the SARS-CoV-2 virus continues to grow. This relatively slow mutation rate for SARS-CoV-2 make us hopeful that investigational SARS-CoV-2 vaccine candidates will potentially have one less hurdle toward offering the ability to provide protection over a longer period of time.

Influenza viruses undergo antigenic shift, an abrupt, major change in the virus’s antigens that happens less frequently than antigenic drift. It occurs when two different, but related, influenza virus strains infect a host cell at the same time. Because influenza virus genomes are formed by 8 separate pieces of RNA (called “genome segments”), sometimes these viruses can “mate,” in a process called, “reassortment.” During reassortment, two influenza viruses’ genome segments can combine to make a new strain of influenza virus.

 

https://www.pfizer.com/news/articles/how_do_viruses_mutate_and_what_it_means_for_a_vaccine

 

Lab Leak Plausible(Critical Review)[2021]

Holmes et al. have written an extensive argument for a natural origin of SARS-CoV-2 and importantly urge a comprehensive, collaborative, and careful investigation of possible zoonotic origins of the virus. However, their review does not address plausible lab origin scenarios where a virus may have infected a researcher during fieldwork or in the lab. It is too confident in dismissing the possibility that the virus may have been cultured, manipulated, and even engineered or recombined in the laboratory without leaving obvious signs of human interference. Techniques to synthesize entire virus genomes without leaving traces have existed for years and have been used by labs around the world; these can easily evade detection strategies devised by scientists, especially when not all viruses and sequences being studied in labs are shared publicly in a timely manner [80,81].

 

https://ayjchan.medium.com/a-response-to-the-origins-of-sars-cov-2-a-critical-review-5d4a644d9777

 

Cloth Masks Dont Work (CNN)[2021]

As the highly contagious Omicron coronavirus variant continues to spread, some experts say it's past time to reconsider your face mask options -- especially if you're still wearing the cloth variety.

"Cloth masks are little more than facial decorations. There's no place for them in light of Omicron," said CNN Medical Analyst Dr. Leana Wen, an emergency physician and visiting professor of health policy and management at the George Washington University Milken Institute School of Public Health, on CNN Newsroom Tuesday. "This is what scientists and public health officials have been saying for months, many months, in fact," Wen added in a separate phone interview.
Omicron is now the dominant strain of coronavirus in the US, according to the CDC
"We need to be wearing at least a three-ply surgical mask," she said, which is also known as a disposable mask and can be found at most drugstores and some grocery and retail stores. "You can wear a cloth mask on top of that, but do not just wear a cloth mask alone."
https://www.cnn.com/2021/12/24/health/cloth-mask-omicron-variant-wellness/index.html

Ivermectin is Effective Against COVID(Meta Studies)[2021]

Background: Ivermectin has demonstrated different mechanisms of action that potentially protect from both coronavirus disease 2019 (COVID-19) infection and COVID-19-related comorbidities. Based on the studies suggesting efficacy in prophylaxis combined with the known safety profile of ivermectin, a citywide prevention program using ivermectin for COVID-19 was implemented in Itajaí, a southern city in Brazil in the state of Santa Catarina. The objective of this study was to evaluate the impact of regular ivermectin use on subsequent COVID-19 infection and mortality rates.

https://www.cureus.com/articles/82162-ivermectin-prophylaxis-used-for-covid-19-a-citywide-prospective-observational-study-of-223128-subjects-using-propensity-score-matching

https://c19ivermectin.com/

https://ivmmeta.com/

 

Booster Shot Effective for 10 Weeks Against Omicron(UKHSA)[2021]

Booster protection against symptomatic illness caused by the Omicron variant dropped by up to 25% within 10 weeks, new real-world data found — though it's not yet clear whether everyone may need further doses in 2022.

 

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1043807/technical-briefing-33.pdf

https://www.businessinsider.com/how-long-does-booster-protection-omicron-covid-last-study-2021-12

 

 

Ivermectin Leads to 90% Reduction in COVID Mortality Rate(Study)[2022]

Strictly regular use of ivermectin as prophylaxis for COVID-19 leads to a 90% reduction in COVID-19 mortality rate, in a dose-response manner: definitive results of a prospective observational study of a strictly controlled 223,128 population from a city-wide program in Southern Brazil

https://www.researchgate.net/publication/358386329_Strictly_regular_use_of_ivermectin_as_prophylaxis_for_COVID-19_leads_to_a_90_reduction_in_COVID-19_mortality_rate_in_a_dose-response_manner_definitive_results_of_a_prospective_observational_study_of_a